Crossing Over: Cells Move Through an Epithelial Bridge
Crossing Over: Cells Move Through an Epithelial Bridge
Collections: Image Award Winners, Metastasis
2012 Award Winner
Brett Zani
Edelman Lab
Koch Institute at MIT, Harvard-MIT Division of Health Sciences and Technology
Epi-Fluorescence Micrograph
The long, thin structure shown here was discovered entirely by accident. Researchers were conducting tissue engineering experiments when they began noticing “bridges” like this one connecting populations of epithelial cells in culture. The physiological significance of these bridges remains unknown, but in the Petri dish they seem to enable a new form of cell migration.
Video
Brett Zani explains how and why he captured this image of an epithelial bridge.