Snap ChAT: A Flatworm Creates a New Profile
Snap ChAT: A Flatworm Creates a New Profile
Collections: Image Award Winners
2017 Award Winner
Samuel A. LoCascio, Kutay Deniz Atabay, Peter Reddien
MIT Department of Biology, MIT Department of Brain and Cognitive Sciences, Whitehead Institute
The planarian flatworm shown here possesses a remarkable ability to regenerate complex tissue structures lost to injury, including a brain and eyes. Each color represents a different layer of neurons in the head, revealed by expression of the choline acetyltransferase (ChAT) gene. Not shown in this image are the abundant stem cells that give rise to a new central nervous system as the flatworm regenerates. The Reddien Lab studies planarians to illuminate the cellular and molecular basis of regeneration.