Capture the Flags: Monitoring Disease-Associated Immune Activity
Capture the Flags: Monitoring Disease-Associated Immune Activity
Collections: Image Award Winners, Cancer Immunology & Immunotherapy, The Bridge Project
2023 Award Winner
Sasan Jalili, Ryan Hosn, Julian Rojo, David Mankus, Margaret Bisher, Abigail Lytton-Jean, Paula T. Hammond, Darrell J. Irvine
Koch Institute at MIT
A microneedle patch developed by the Hammond and Irvine Labs non-invasively samples biomarkers and immune cell populations in skin. By analyzing the cells and surrounding tissue, researchers aim to classify the immune signatures of various disease stages, including autoimmune skin conditions and hard-to-detect ovarian cancers.
Highlighted here are immune cells (colored purple to represent gender equity and women’s health) collected by the needles’ seaweed-based coating (gray). The device is now being used in preclinical and clinical settings on three continents.
Video
Sasan Jalili presents on his image.