Wearing your Brain on Your Sleeve 

Wearing your Brain on Your Sleeve 

Juana De La O, Chidera Okeke, Adam C. Martin, Martin Lab, Building 68

During development, tissues are pushed, pulled, and folded into complex shapes. The brain begins as a flat sheet of cells, called the neural plate, that folds and zips up into a neural tube. The neural plate has a network of force producing filaments on its surface that helps fold it into the neural tube. To understand how the network promotes neural tube folding, we created the first high-resolution map of the filaments across the entire folding neural tube. We are now using the pattern of filaments from this map to build a theory describing how the neural tube folds.

Valentine heart shaped red shape slightly illuminated.

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