Polyamines are metabolites which can extend lifespan. They are involved in cancer, neurodegeneration and immunity. We have made a tool to visualize polyamines in any biological system which will uncover their mechanism of action, which remain undiscovered to date.

This image shows how polyamines vary in a complex tissue such as intestinal organoids. We learnt that stem cells have much higher polyamines than their differentiated state, suggesting polyamines may have important role in regeneration.